Mission Bay & SoMa is a prime-tier Class A submarket of San Francisco with average asking rent around $80/sqft/yr.
Tech-led southern submarket. · Tier: prime · Avg rent: $80/sqft/yr
Mission Bay and SoMa together form the city's tech and biotech corridor. Mission Rock anchors recent Class A delivery; UCSF and Chase Center anchor the broader Mission Bay cluster.
Biotech, technology, consumer-internet, gaming.
30-50,000 sqft floor plates with lab-ready capability in select assets.
Caltrain 4th & King, Muni Metro T-Third, Central Subway.
Caltrain anchor for Peninsula commuters.
Chase Center, Crane Cove Park, Oracle Park.
Mission Bay & SoMa is one of 6 Class A submarkets we cover in San Francisco, classified as prime tier with an average asking rent around $80/sqft/yr. Compared with the broader San Francisco Class A stock, Mission Bay & SoMa typically attracts Biotech, technology, consumer-internet, gaming and competes most directly with the city's other prime submarkets on building specification, transit access, and amenitisation.
Adjacent submarkets to study alongside Mission Bay & SoMa: Transbay, Financial District, Jackson Square, Mission Bay. The full San Francisco submarket atlas is at /cities/san-francisco.
For an institutional Class A occupier evaluating Mission Bay & SoMa, the highest-leverage analyses to commission next are the rent benchmark, the concession-package comparable, and the ESG performance baseline. Class A Atlas covers each as a dedicated topic page for this submarket:
Terminology specific to San Francisco Class A leasing and to the prime tier: Class A, Trophy asset, Effective rent, Concession package, TI allowance, Submarket tier.
Reviewed by Miriam Hollander — Lead market analyst. Last updated 2026-04-15. See our methodology and editorial standards.