Boston Class A office rents around 78 USD/sqft/yr (78 USD), with 19.5% vacancy and 18 months of typical rent-free on a 10-year term.
Cambridge / Kendall Square hold the world's deepest life-sciences cluster.
Seaport delivered a wave of new Class A — now in lease-up.
Office vacancy 18-22% in the CBD; lab vacancy structurally tighter.
Lease-up rent-free of 18-24 months on a 10-year term.
ESG retrofits accelerating across older CBD stock.
Boston Class A Office Market
Life sciences capital — and a deep traditional CBD.
TL;DR
Cambridge / Kendall Square hold the world's deepest life-sciences cluster.
Seaport delivered a wave of new Class A — now in lease-up.
Office vacancy 18-22% in the CBD; lab vacancy structurally tighter.
Lease-up rent-free of 18-24 months on a 10-year term.
ESG retrofits accelerating across older CBD stock.
Overview
Boston combines the deepest life-sciences cluster in the world with a traditional financial-and-legal CBD. Lab space drives marginal demand; Class A office is mid-cycle through a softer reset.
Market snapshot
Class A rent
78 USD/sqft/yr (78 USD)
Vacancy
19.5%
Typical lease length
10 years
Typical rent-free
18 months
Composite Q1 2026 Boston Class A and lab reports.
Lease norms
Modified-gross with op-ex escalations. Rent-free 18-24 months on 10-year term standard. Lab leases carry distinct economics — base rent plus operating expenses plus utilities pass-through.
Transit & access
MBTA subway, commuter rail, and Logan Airport access. Silver Line connects the Seaport to South Station.
Tax
Combined federal + Massachusetts corporate tax 28%.
Talent
Deepest STEM and life-sciences talent pool in the US — anchored by MIT, Harvard, BU. Average all-in compensation indexes 95.
Why is Cambridge / Kendall Square so dominant in life sciences?
MIT and Harvard adjacency, plus 30 years of cumulative cluster effects across pharma, biotech, and venture capital, have created the densest life-sciences talent and capital pool in the world.